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American Airlines & American Eagle USA + Canada routes
1. from Dallas/Fort Worth hub
2. from Chicago O'Hare hub
3. from Miami hub
4. from New York La Guardia & JFK
5. from Boston & Raleigh/Durham
6. from Los Angeles
7. from San Francisco & San Jose

American Airlines & American Eagle international routes
8.  Caribbean - from San Juan hub, Puerto Rico
9.  Caribbean - from US mainland hubs & focus cities
10. Mexico & Central America

American Airlines international routes
11. South America
12. Europe & Asia

former American Connection routes
13. from St.Louis
14. Chautauqua Airlines
15. Trans States Airlines
16. Great Lakes Aviation
17. Regionsair

American Airlines major codeshare partners worldwide
18. Alaska Airlines via Seattle to cities along US West Coast
19. British Airways via London to Europe, Africa & West Asia
20. Brussels Airlines via Brussels to Europe & Africa
21. Swiss via Zurich to Europe, Africa & Middle East
22. Japan Airlines via Tokyo to the Far East & Japan domestic
23. Cathay Pacific via Hong Kong to the Far East
24. Qantas on trans-pacific routes and Australia domestic
25. Mexicana on USA-Mexico routes
26. TAM via Sao Paulo on Brazil domestic
27. LAN via Santiago on Chile domestic
28. Gulf Air via London/Frankfurt/Paris to the Middle East